Ovarian cancer in female-to-male transsexuals: report of two cases
Hage JJ, Dekker JJ, Karim RB, Verheijen RH, Bloemena E.
Department of Plastic and Reconstructive Surgery,
Academisch Ziekenhuis Vrije Universiteit,
Amsterdam, The Netherlands.
Abstract [Full Text] [PDF]
Background Ovarium cancer is the fifth most common cause of cancer-related death in women and is the most common fatal gynecologic malignancy. So far, ovarium carcinoma has not been reported to have occurred in female-to-male transsexuals.
Objective and Method We report on two such cases. Long-term exposure to increased levels of endogenous and exogenous androgens is hypothesized to constitute an additional risk factor in transsexuals as it has been associated with ovarian epithelian cancer.
Conclusion Simultaneous salpingo-oophorectomy should be performed in any female-to-male transsexual undergoing hysterectomy in the course of gender-confirming therapy. Copyright 2000 Academic Press.
Citation: Gynecol Oncol 2000 Mar;76(3):413-5 an article published on the Internet by PubMed <http://www.ncbi.nlm.nih.gov/>